Spontaneous hypoparathyroidism: clinical, biochemical and radiological features.
Indian J Pediatr
;
1989 Mar-Apr; 56(2): 267-72
Article
Dans Anglais
| IMSEAR
| ID: sea-84318
ABSTRACT
The clinical, biochemical and radiological features of spontaneously occurring hypoparathyroidism in 13 patients (mean age 9 years, range 4 months to 20 years) are highlighted. Nine patients presented with a history of generalised seizures and 2 were in acute hypocalcemic crisis at the time of admission. Ocular involvement (corneal opacities, cataract) was present in 3 patients and vitiligo in 1 patient. The serum calcium level was low (mean 5.46 mg/dl, range 5.0-7.2) and serum phosphorus level was high (mean 8.49 mg/dl, range 6-14 mg/dl) in all the patients. Six patients had elevated serum alkaline phosphatase (greater than 20 KAU). Radiological examination revealed osteopenia in 3 patients. Nine patients underwent a head CT scan; 5 had evidence of basal ganglia calcification. The findings of elevated serum alkaline phosphatase and osteopenia are at variance with existing literature and may possibly reflect pre-existing vitamin D deficiency.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Crises épileptiques
/
Affections des ganglions de la base
/
Maladies osseuses métaboliques
/
Femelle
/
Humains
/
Mâle
/
Calcinose
/
Enfant
/
Adolescent
/
Adulte
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Indian J Pediatr
Année:
1989
Type:
Article
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