Surrogate endpoints: do they really contribute in therapeutic decision making?
Article
Dans Anglais
| IMSEAR
| ID: sea-87141
ABSTRACT
Surrogate endpoints are substitutes for the true endpoints and measured in any clinical research to relate in some way to the outcome of primary interest. Inappropriate selection of surrogate markers may lead to controversies during clinical trials or therapeutic interventions. Use of surrogate markers depends upon thorough understanding of the pathophysiology of the disease and pharmacology of drugs. Results obtained with surrogates should be regarded as preliminary and necessitates definitive studies.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Plan de recherche
/
Humains
/
Collecte de données
/
Essais cliniques comme sujet
/
Interprétation statistique de données
Type d'étude:
Étude pronostique
langue:
Anglais
Année:
1999
Type:
Article
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