Short term study on relative merits of acetate and bicarbonate dialysis.
Article
Dans Anglais
| IMSEAR
| ID: sea-89651
ABSTRACT
We did a double blind, crossover, prospective study comparing bicarbonate and acetate containing solutions in haemodialysis. Thirty stable patients with end stage renal disease on maintenance haemodialysis while awaiting a renal transplant were each studied on three dialysis with acetate and three with bicarbonate. Nine patients developed symptoms like headache, nausea, vomiting, giddiness, and malaise and developed hypotension during acetate dialysis and three patients during bicarbonate dialysis. There were symptoms during 16.66% of acetate dialysis sessions and 5.55% of bicarbonate dialysis sessions. (P less than 0.05). There was a statistically significant decrease in PaO2 and PaCO2 on acetate dialysis at 30 minutes after initiation of dialysis. There was no significant difference in weight loss on dialysis, or in blood pressure and correction of acidosis. We conclude that bicarbonate dialysis is better tolerated, but acetate intolerance is not a major problem since we use small surface area dialysers (0.8 M2).
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Hydrogénocarbonates
/
Femelle
/
Humains
/
Mâle
/
Solutions d'hémodialyse
/
Méthode en double aveugle
/
Adolescent
/
Dialyse rénale
/
Adulte
/
Défaillance rénale chronique
Type d'étude:
Essai clinique contrôlé
/
Étude observationnelle
langue:
Anglais
Année:
1991
Type:
Article
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