Renal involvement in multiple myeloma.
Article
Dans Anglais
| IMSEAR
| ID: sea-91249
ABSTRACT
The present study is a retrospective chart analysis of 33 patients who satisfied the diagnostic criteria of multiple myeloma. Sixteen (49.5%) of these 33 patients developed renal failure at some point in time. The mean age +/- 1SD of patients who developed renal failure was 59.2 +/- 13 years (range 34-85 years). There were 12 males and 4 females. The precipitating factors for renal failure were dehydration (12.5%), hypercalcemia (62.5%) and use of non-steroidal antiinflammatory drugs (6.2%). Hypercalcemia was observed in 10 of the 16 patients who developed renal failure while it was seen in only 4 of the 17 cases who did not develop renal failure (relative risk 5.4). In 11 (68.7%) patients, the renal function improved with hydration, treatment of hypercalcemia and chemotherapy. The 1 and 3 year actuarial survival of patients with renal failure and multiple myeloma was 87% and 74% respectively.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Sujet âgé de 80 ans ou plus
/
Sujet âgé
/
Femelle
/
Humains
/
Mâle
/
Études rétrospectives
/
Adulte
/
Insuffisance rénale
/
Adulte d'âge moyen
/
Myélome multiple
Type d'étude:
Etude d'étiologie
/
Étude observationnelle
Limites du sujet:
Aged80
langue:
Anglais
Année:
1996
Type:
Article
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