2-CdA in the treatment of hairy cell leukaemia.
Article
Dans Anglais
| IMSEAR
| ID: sea-91940
ABSTRACT
INTRODUCTION:
Hairy cell leukaemia (HCL) is a rare lymphoproliferative disorder. Treatment options available are splenectomy, interferon, DCF and 2-CdA. 2-CdA is considered to have curative potential as proved by the other studies.METHODS:
We gave 2-CdA in a dose of 0.09/kg/day as a continuous infusion in sixteen patients of hairy cell leukaemia.RESULTS:
Three patients developed neutropenia post transfusion. At the end of three months all patients were in remission. Two patients relapsed at the median follow-up of 15 months.CONCLUSION:
2-CdA in HCL can achieve complete remission, prolonged survival and care as well.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Femelle
/
Humains
/
Mâle
/
Leucémie à tricholeucocytes
/
Chloro-2 adénosine
/
Désoxyadénosine
/
Taux de survie
/
Résultat thérapeutique
/
Adulte
/
Adulte d'âge moyen
langue:
Anglais
Année:
2001
Type:
Article
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