Outcome in West syndrome.
Indian Pediatr
;
2008 Jul; 45(7): 559-63
Article
Dans Anglais
| IMSEAR
| ID: sea-9195
ABSTRACT
OBJECTIVES:
To assess the seizure and developmental outcome in children with West syndrome with respect to treatment lag.METHODS:
Twenty-six children satisfying inclusion criteria of West syndrome i.e., infantile spasms, psychomotor retardation and abnormal EEG pattern were prospectively evaluated. Response to treatment was assessed based on seizure control, EEG, developmental assessment and parental observations.RESUltS:
The time lag from onset of seizures to appropriate treatment was <1 month in 11 children; 1-6 months in 8 children; and >6 months in 7 children. Children with treatment lag <1 month fared better than those who had a large treatment lag (P<0.05). Children with good seizure control also showed better developmental improvement (P<0.05).CONCLUSION:
Children with West syndrome have better seizure control and development, if the treatment is started within 1 month of onset of symptoms.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Spasmes infantiles
/
Indice de gravité de la maladie
/
Encéphale
/
Femelle
/
Humains
/
Mâle
/
Enfant d'âge préscolaire
/
Études prospectives
/
Acide valproïque
/
Troubles de la cognition
Type d'étude:
Étude observationnelle
langue:
Anglais
Texte intégral:
Indian Pediatr
Année:
2008
Type:
Article
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