Rapid immunodiagnosis of active cytomegalovirus infection by pp65 antigenemia assay.
Bangladesh Med Res Counc Bull
;
2006 Apr; 32(1): 22-8
Article
Dans Anglais
| IMSEAR
| ID: sea-92
ABSTRACT
Detection of early antigen PP65 in blood leucocytes is a new method of diagnosing active cytomegalovirus (CMV) infection. Using a mixture of two monoclonal antibodies, CMV pp65 antigen was detected in blood leucocytes by a quantitative indirect immunofluorescence test within 3-5 hours after sampling. The pp65 antigen was detected in 20(29.8%) of the 67 immunocompromised patients included in this study. The level of CMV antigenemia appears to be related to the severity of CMV infection. Thus, this method may provide a rapid and sensitive approach to early diagnosis of active CMV infection in immunocompromised patients and a promising marker for initiating therapy and monitoring disease activity and its response to therapy.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Phosphoprotéines
/
Bangladesh
/
Tests immunologiques
/
Humains
/
Protéines de la matrice virale
/
Infections à cytomégalovirus
/
Diagnostic précoce
Type d'étude:
Etude diagnostique
/
Étude de dépistage
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Bangladesh Med Res Counc Bull
Année:
2006
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS