Effect of intravenous quinine on capillary glucose levels in malaria.
Article
Dans Anglais
| IMSEAR
| ID: sea-93308
ABSTRACT
OBJECTIVE:
Hypoglycemia occurring during management in patients of severe malaria is often overlooked, which can be associated with higher morbidity and mortality rates.METHOD:
Capillary glucose was estimated in 32 patients of malaria before, at one hour and at six hours of quinine administration. Quinine was given in saline solution intravenously.RESULTS:
Pretreatment capillary glucose was found to be lower (71-80 mg/dl) in 12.5% cases. After one hour of intravenous quinine administration, capillary glucose levels fell by 11.84% in all the cases. A further fall of 20.50% was observed in 75% of cases after six hour. Two patients died and both were suffering from cerebral malaria. Statistically, fall in capillary glucose was highly significant at one hour (t=9.4, p < 0.001) and at six hours. (t=3.87, p < 0.001)CONCLUSION:
Statistically significant fall in capillary glucose levels has been observed in patients of malaria with quinine administration.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Quinine
/
Glycémie
/
Femelle
/
Humains
/
Mâle
/
Vaisseaux capillaires
/
Taux de survie
/
Probabilité
/
Études de suivi
/
Paludisme à Plasmodium vivax
Type d'étude:
Etude d'étiologie
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Pays comme sujet:
Asie
langue:
Anglais
Année:
2001
Type:
Article
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