Clinicopathological study of clinically undiagnosed cases of kala-azar with special reference to grading of parasites.
J Indian Med Assoc
;
1995 Mar; 93(3): 87-9
Article
Dans Anglais
| IMSEAR
| ID: sea-97980
ABSTRACT
Clinicopathological study of 34 clinically undiagnosed cases of kala-azar has been undertaken with a view to establish the diagnosis and correlate the quantitative grading of Leishmania donovani in bone marrow/splenic aspirates with clinical features and duration of disease. The ages of the patients were between 5 and 45 years. The duration of illnesses ranged from 2-24 months with 47% having 2 months' duration. Splenomegaly was less than 7 cm in 70.5% cases. Anaemia, leucopenia and mild thrombocytopenia were present in all the cases. Aldehyde test was positive in 47% cases. Bone marrow aspiration revealed the parasites in 82.3% cases. L donovani was also observed in 66.6% cases of splenic aspiration including 6 cases where bone marrow failed to reveal the parasite. Grading of the parasites in bone marrow and splenic aspirates revealed majority of the cases (73.5%) were in 3+ and 4+ grades. No correlation between splenic size and duration of illness or parasite grading was detected. Neither any positive correlation between parasite grading and duration of illness was observed.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Rate
/
Moelle osseuse
/
Leishmania donovani
/
Femelle
/
Humains
/
Mâle
/
Enfant
/
Facteurs sexuels
/
Adolescent
/
Adulte
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
J Indian Med Assoc
Année:
1995
Type:
Article
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