Prevalence, haemolytic and haemagglutination activities and antibiotic susceptibility profiles of Campylobacter spp. isolated from human diarrhoeal stools in Vhembe District, South Africa.
J Health Popul Nutr
;
2007 Dec; 25(4): 406-13
Article
Dans Anglais
| IMSEAR
| ID: sea-985
ABSTRACT
Campylobacter species are increasingly being recognized as agents of gastroenteritis worldwide. However, data on the pathogenic characteristics of the organism isolated in rural communities in South Africa are lacking. In this study, the prevalence of Campylobacter spp. from diarrhoeal stools, haemolytic and haemagglutinating activities of the isolates, and antibiotic susceptibility profiles, including minimum inhibitory concentration (MIC) patterns to different antibiotics, were determined using the standard microbiological techniques. Campylobacter spp. were isolated from individuals of all age-groups; however, the infection rate was higher among individuals aged less than two years (30.4%). Of 115 Campylobacter strains isolated, polymerase chain reaction (PCR) analysis indicated that 98 (85%) were C. jejuni, while 17 (15%) were C. coli. Seventy-one (62%) of the strains showed haemolysis on human blood, and 80% agglutinated human blood, whereas 22.6% were beta-lactamase-positive. Resistance to antimicrobials, such as erythromycin, ciprofloxacin, vancomycin, and fusidic acid, was high. Increased resistance to macrolide and quinolone antibiotics poses major risks for treatment failure. Haemolytic and haemagglutinating activities may be useful in preliminary characterization of pathogenic strains in settings where Campylobacter-associated infections are common.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
République d'Afrique du Sud
/
Sujet âgé
/
Femelle
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Humains
/
Mâle
/
Campylobacter
/
Infections à Campylobacter
/
Nouveau-né
/
Numération de colonies microbiennes
/
Tests de sensibilité microbienne
Type d'étude:
Étude de prévalence
/
Facteurs de risque
Pays comme sujet:
Afrique
langue:
Anglais
Texte intégral:
J Health Popul Nutr
Thème du journal:
Gastroenterology
/
Nutritional Sciences
/
Public Health
Année:
2007
Type:
Article
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