Quantitation of proteinuria using protein-creatinine ratio in random urine samples.
Indian Pediatr
;
1991 May; 28(5): 463-7
Article
Dans Anglais
| IMSEAR
| ID: sea-9956
ABSTRACT
Estimation of proteinuria in children is cumbersome when a 24 h urine collection is needed. In the presence of a stable glomerular filtration rate, the ratio of urinary protein and creatinine should reflect the protein excretion. One hundred samples of urine (24 h and random samples) were collected from 50 children with nephrotic syndrome, 25 with nephrotic syndrome in remission and 25 normal children. The 24 h urine total protein and random urine protein-creatinine ratio were assessed on these samples. Linear regression analysis of the results showed excellent correlation between the values (r = 0.81, p less than 0.001). A random urine protein-creatinine ratio of greater than 3.5 correlated with massive proteinuria, while a ratio less than 0.2 was suggestive of physiological values. The sensitivity, specificity, positive and negative predictive values of the protein-creatinine ratio in massive proteinuria were very high. We conclude that the random urine protein-creatinine ratio can be used reliably to assess the degree of proteinuria in children.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Protéinurie
/
Valeurs de référence
/
Manipulation d'échantillons
/
Humains
/
Enfant
/
Analyse de régression
/
Rythme circadien
/
Créatinine
/
Faux négatifs
/
Syndrome néphrotique
Type d'étude:
Essai clinique contrôlé
/
Etude diagnostique
/
Étude pronostique
langue:
Anglais
Texte intégral:
Indian Pediatr
Année:
1991
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS