Relationship between rapid eye movement sleep and incidence of angina pectoris in different genders / 西安交通大学学报(医学版)

ABSTRACT

【Objective】 To investigate the relationship between rapid eye movement sleep (REM) and the incidence of angina pectoris (AP) in different genders. 【Methods】 We recruited 2710 participants from the Sleep Heart Health Study with an average age of (61.7±10.9)y, of whom 1 103 (40.7%) were male and 1 607(59.3%) were female. The participants were divided into grade 1 (25%) according to the percentage of REM sleep time (REM%). Complete polysomnography data and medical records were collected for all the participants. Multivariate logistic regression analysis was used to characterize the independent association between REM% and the occurrence of AP. 【Results】 REM% in the three groups varied significantly in age, body mass index (BMI), smoking, AHI, diabetes, and hypertension (P25% in women was closely related to AP (OR=1.523; 95% CI1.132-2.051, P=0.006). 【Conclusion】 Participants with REM sleep time >25% have a significantly increased prevalence of AP in women, but not in men.