Research Progress of Post-Transplant Cyclophosphamide Combined with Antithymocyte Globulin in Preventing GVHD after Hematopoietic Stem Cell Transplantation --Review / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 1899-1904, 2023.
Article
Dans Zh
| WPRIM
| ID: wpr-1010057
Responsable en Bibliothèque :
WPRO
ABSTRACT
Graft-versus-host disease (GVHD) is one of the major complications after allogeneic hematopoietic stem cell transplantation (allo-HSCT), which seriously affects the prognosis of patients. At present, a new regimen of post-transplantation cyclophosphamide (PTCy) combined with antithymocyte globulin (ATG) has been used to prevent GVHD, indicating that PTCy combined with ATG may have a good effect on the prevention of GVHD in different types of transplantation. However, the mechanism of this regimen, its effect on immune reconstitution and viral reactivation still needs to be further studied. Therefore, this article briefly reviews the research progress of PTCy combined with ATG in preventing GVHD after HSCT.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Transplantation homologue
/
Études rétrospectives
/
Transplantation de cellules souches hématopoïétiques
/
Cyclophosphamide
/
Maladie du greffon contre l'hôte
/
Sérum antilymphocyte
Limites du sujet:
Humans
langue:
Zh
Texte intégral:
Journal of Experimental Hematology
Année:
2023
Type:
Article