Research Progress of LncRNA SNHGs in Regulating the Biological Behavior
of Non-small Cell Lung Cancer / 中国肺癌杂志
Chinese Journal of Lung Cancer
;
(12): 851-862, 2023.
Article
Dans Chinois
| WPRIM
| ID: wpr-1010093
ABSTRACT
Lung cancer is one of the malignant tumors with the highest incidence and mortality rate in China, and its occurrence and development mechanism and treatment methods are the current research focuses. In recent years, the emergence of drugs targeting various tumor driver genes has significantly improved patients' survival and quality of life, setting off a wave of research on new therapeutic targets. Among them, long non-coding RNA (lncRNA) plays a crucial role in the malignant behavior of tumors, which has attracted widespread attention. Shown by a large number of studies, partial members of lncRNA small nucleolar RNA host gene (SNHG) family are aberrantly expressed in many maliglant tumors including non-small cell lung cancer (NSCLC) and participate in cell proliferation, invasion and migration, which may act as a new diagnostic and prognostic biomarker and can be a therapeutic target of NSCLC. In this review, we comprehensively summarize and explore the recent investigation of SNHGs in NSCLC in order to provide new ideas for the diagnosis and treatment of NSCLC.
.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Qualité de vie
/
Régulation de l'expression des gènes tumoraux
/
Mouvement cellulaire
/
Chine
/
Carcinome pulmonaire non à petites cellules
/
MicroARN
/
Lignée cellulaire tumorale
/
Prolifération cellulaire
/
ARN long non codant
/
Tumeurs du poumon
Limites du sujet:
Humains
Pays comme sujet:
Asie
langue:
Chinois
Texte intégral:
Chinese Journal of Lung Cancer
Année:
2023
Type:
Article
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