Role of cytoplasmic lncRNAs in regulating cancer signaling pathways / 浙江大学学报(英文版)(B辑:生物医学和生物技术)
Journal of Zhejiang University. Science. B
;
(12): 1-8, 2019.
Article
Dans Anglais
| WPRIM
| ID: wpr-1010438
ABSTRACT
Cancer remains a serious healthcare problem despite significant improvements in early detection and treatment approaches in the past few decades. Novel biomarkers for diagnosis and therapeutic strategies are urgently needed. In recent years, long noncoding RNAs (lncRNAs) have been reported to be aberrantly expressed in tumors and show crosstalk with key cancer-related signaling pathways. In this review, we summarized the current progress of research on cytoplasmic lncRNAs and their roles in regulating cancer signaling and tumor progression, further characterization of which may lead to effective approaches for cancer prevention and therapy.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Transduction du signal
/
Marqueurs biologiques tumoraux
/
Protein-Serine-Threonine Kinases
/
Phosphatidylinositol 3-kinases
/
Cytoplasme
/
Protéines proto-oncogènes c-akt
/
Sous-unité alpha du facteur-1 induit par l'hypoxie
/
ARN long non codant
/
Voie de signalisation Hippo
/
Tumeurs
Limites du sujet:
Animaux
/
Humains
langue:
Anglais
Texte intégral:
Journal of Zhejiang University. Science. B
Année:
2019
Type:
Article
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