Diagnostic value of alcoholic liver disease (ALD)/nonalcoholic fatty liver disease (NAFLD) index combined with γ-glutamyl transferase in differentiating ALD and NAFLD
The Korean Journal of Internal Medicine
;
: 479-487, 2016.
Article
Dans Anglais
| WPRIM
| ID: wpr-101299
ABSTRACT
BACKGROUND/AIMS:
This study aimed to verify the reliability of the alcoholic liver disease (ALD)/nonalcoholic fatty liver disease (NAFLD) index (ANI) for distinguishing ALD in patients with hepatic steatosis from NAFLD, and to investigate whether ANI combined with γ-glutamyl transferase (GGT) would enhance the accuracy of diagnosis in China.METHODS:
A hundred thirty-nine cases of fatty liver disease (FLD) were divided into two groups of ALD and NAFLD. The ANI was calculated with an online calculator. All indicators and ANI values were analyzed using statistical methods.RESULTS:
ANI was significantly higher in patients with ALD than in those with NAFLD (7.11 ± 5.77 vs. -3.09 ± 3.89, p 0.05).CONCLUSIONS:
ANI can help distinguish ALD from NAFLD with high accuracy; when ANI was combined with GGT, its effectiveness improved further.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Aspartate aminotransferases
/
Transferases
/
Chine
/
Courbe ROC
/
Sensibilité et spécificité
/
Diagnostic
/
Diagnostic différentiel
/
Index érythrocytaires
/
Stéatose hépatique
/
Alcooliques
Type d'étude:
Etude diagnostique
/
Étude pronostique
Limites du sujet:
Humains
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
The Korean Journal of Internal Medicine
Année:
2016
Type:
Article
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