Radiosensitizing effect of PARP-1 inhibitor Olaparib on MCF-7 breast cancer and hypoxic imaging / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12): 1668-1674, 2023.
Article
Dans Chinois
| WPRIM
| ID: wpr-1013714
ABSTRACT
Aim To investigate the radiosensitizing effect of the PARP inhibitor Olaparib on MCF-7 breast cancer model and to monitor the radiosensitizing effect of Olaparib by F-Fluoroerythronitroimidazole (F-FETNIM) PET/CT. Methods MCF-7 breast cancer model was established and divided into control group, Olaparib group, irradiation group and Olaparib + irradiation group according to random number table method; tumor volume was measured to calculate tumor inhibition rate and survival time of tumor-bearing mice was counted.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Pharmacological Bulletin
Année:
2023
Type:
Article
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