Cyclovirobuxine D ameliorates aldosterone-induced primary neonatal rat cardiac myocyte injury via Ca

Guang-Qiong ZHANG; Sheng-Quan WANG; Ling-Yun FU; Yi-Ni XU; Hong LUO; Ling TAO; Xiang-Chun SHEN; Ling LI; Guang-Qiong ZHANG; Sheng-Quan WANG; Ling-Yun FU; Yi-Ni XU; Hong LUO; Ling TAO; Xiang-Chun SHEN; Ling LI

Cyclovirobuxine D ameliorates aldosterone-induced primary neonatal rat cardiac myocyte injury via Ca / 中国药理学通报

Guang-Qiong ZHANG; Sheng-Quan WANG; Ling-Yun FU; Yi-Ni XU; Hong LUO; Ling TAO; Xiang-Chun SHEN; Ling LI; Guang-Qiong ZHANG; Sheng-Quan WANG; Ling-Yun FU; Yi-Ni XU; Hong LUO; Ling TAO; Xiang-Chun SHEN; Ling LI.

Chinese Pharmacological Bulletin ; (12): 564-570, 2021.

Article de Zh | WPRIM | ID: wpr-1014399

Bibliothèque responsable: WPRO

ABSTRACT

ABSTRACT

Aim To investigate the protective effect of cyclovirobuxine D(CVB-D) on aldosterone (ALD)-induced primary neonatal rat cardiac myocytes (PNRC-Ms) injury and the possible mechanism. Methods PNRCMs were extracted by trypsin, and the PNRCMs injury model was established by ALD (10 μmol · L

Mots clés

aldosterone; apoptosis; calcium ion; CaMK II; cyclovirobuxine D; myocardial cell injury

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Texte intégral: 1 Indice: WPRIM langue: Zh Texte intégral: Chinese Pharmacological Bulletin Année: 2021 Type: Article

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