Resection and Partial Liver Segment 2/3 Transplantation with Delayed Total Hepatectomy(RAPID)Procedure for Malignant Liver Tumor / 华中科技大学学报(医学版)

ABSTRACT

Objective Liver transplantation for colorectal cancer patient with liver metastasis has acquired satisfying result,increasing overall survival in selected patients.The scarcity of grafts is a major obstacle in the field of transplant oncology.The use of small segmental auxiliary grafts from deceased or living donors might be a way to expand the donor pool with minimal negative impact for patient on the waiting list for deceased donor transplantation and minimal risk for living donor.RAPID(re-section and partial liver segment 2/3 transplantation with delayed total hepatectomy)procedure combines the advantages of both ALPPS(associating liver partition and portal ligation for staged hepatectomy)and auxiliary liver transplantation and further ex-panded the field of transplant oncology,bringing hope to long term survival for more patients.This review provides an insight into the physiological background for this technique and summarizes technical and surgical considerations,experiences from the past,patient outcomes,existing disputes and the future prospects.Overall,the procedure is complex and risky,with a small number of cases worldwide.Although many patients have achieved good outcomes,it is still insufficient to assess long-term on-cology outcomes.This method is still in the exploratory stage and limited to prospective clinical studies.