A Case of del(16)(q22) in a Patient with Acute Myeloid Leukemia with Complex Karyotype / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 329-333, 2010.
Article
Dans Coréen
| WPRIM
| ID: wpr-102103
ABSTRACT
Inversion of chromosome 16 [inv(16)(p13.1q22)] and t(16;16)(p13.1;q22) are associated with acute myelomonocytic leukemia (AMML) with eosinophilia and a favorable prognosis. On the other hand, patients with del(16)(q22) usually present with MDS or chronic myelomonocytic leukemia (CMML), which can evolve to AMML without eosinophilia, and this chromosomal aberration is associated with older age, a complex karyotype, and a poor prognosis. We report a case of AML with del(16)(q22) which showed a complex karyotype, absence of eosinophilia in bone marrow study and a poor response to chemotherapy.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pronostic
/
Chromosomes humains de la paire 16
/
Leucémie aigüe myéloïde
/
Daunorubicine
/
Délétion de segment de chromosome
/
Hybridation fluorescente in situ
/
Cytarabine
/
Association de médicaments
/
Précurseurs des monocytes et macrophages
/
Caryotypage
Type d'étude:
Étude pronostique
Limites du sujet:
Humains
/
Mâle
langue:
Coréen
Texte intégral:
The Korean Journal of Laboratory Medicine
Année:
2010
Type:
Article
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