A Case of Microscopic Polyangiitis Associated with Paranasal Sinusitis and Pulmonary Hemorrhage / 대한신장학회잡지
Korean Journal of Nephrology
; : 832-837, 2005.
Article
de Ko
| WPRIM
| ID: wpr-102320
Bibliothèque responsable:
WPRO
ABSTRACT
Microscopic polyangiitis is a systemic small-vessel vasculitis primarily associated with necrotizing glomerulonephritis and pulmonary capillaritis. This disease is determined by clinical manifestation, ANCA, and involved organ or renal biopsy. We describe a 49-year-old female presenting with chronic postnasal drip, progressive dyspnea and abrupt hemoptysis. Her serum p-ANCA was postitive, but c- ANCA was negative. Her chest X-ray and chest CT scan showed pulmonary hemorrhage, and the renal biopsy specimen revealed crescentic glomerulonephritis. She was diagnosed as having an ANCA-associated vasculitis, and more specifically, a microscopic polyangiitis accompanied with paranasal sinusitis. She was treated with intravenous methylprednisolone pulse therapy, followed by prednisolone and cyclophosphamide per oral tablets. She showed rapid progression of renal failure and died from sepsis after 2 months of treatment.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Sinusite
/
Comprimés
/
Thorax
/
Vascularite
/
Biopsie
/
Méthylprednisolone
/
Prednisolone
/
Tomodensitométrie
/
Sepsie
/
Anticorps anti-cytoplasme des polynucléaires neutrophiles
Limites du sujet:
Female
/
Humans
langue:
Ko
Texte intégral:
Korean Journal of Nephrology
Année:
2005
Type:
Article