Clinical effects of Shenxie Zhitong Capsules combined with DONG's Extraordinary Points on patients with knee osteoarthritis of Cold-Dampness Obstruction Pattern / 中成药
Chinese Traditional Patent Medicine
; (12): 821-825, 2024.
Article
de Zh
| WPRIM
| ID: wpr-1028774
Bibliothèque responsable:
WPRO
ABSTRACT
AIM To explore the clinical effects of Shenxie Zhitong Capsules combined with DONG's Extraordinary Points on patients with knee osteoarthritis of Cold-Dampness Obstruction Pattern.METHODS Eighty patients were randomly assigned into control group(40 cases)for 1-month intervention of DONG's Qi Point,and observation group(40 cases)for 1-month intervention of both Shenxie Zhitong Capsules and DONG's Qi Point.The changes in clinical effects,TCM syndrome scores,LKSS score,WOMAC score,NRS score,AIMS2-SF score,sIL-4R,TNF-α,HMGBl,TLR-4,BALP,BGP and β-CTX were detected.RESULTS The observation group demonstrated higher total effective rate than the control group(P<0.05).After the treatment,the two groups displayed decreased TCM syndrome scores,WOMAC score,NRS score,sIL-4R,TNF-α,HMGBl,TLR-4,β-CTX(P<0.05),and increased LKSS score,AIMS2-SF score,BALP,BGP(P<0.05),especially for the observation group(P<0.05).CONCLUSION For the patients of Cold-Dampness Obstruction Pattern,Shenxie Zhitong Capsules combined with DONG's Extraordinary Points can inhibit body inflammatory responses,improve bone metabolism,and relieve knee pain and clinical symptoms.
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WPRIM
langue:
Zh
Texte intégral:
Chinese Traditional Patent Medicine
Année:
2024
Type:
Article