Wilms' tumor, aniridia, genitourinary anomalies, and mental retardation (WAGR) syndrome: Successful treatment of the first case with bilateral Wilms' tumors in Korea / 소아과
Korean Journal of Pediatrics
;
: 1355-1358, 2008.
Article
Dans Anglais
| WPRIM
| ID: wpr-103101
ABSTRACT
Wilms' tumor, aniridia, genitourinary anomalies, and mental retardation (WAGR) syndrome is caused by deletion of chromosome 11p13, including the Wilms' tumor (WT1) and aniridia gene (PAX6) loci. Here, we report the first case of WAGR syndrome in Korea; the patient was a 2-year-old girl with bilateral aniridia from birth who presented with abdominal distention and mental retardation. Cytogenetically, she had deletion of chromosome 11p11.2-13. Bilateral Wilms' tumors were successfully treated by chemotherapy and surgery. She has been tumor-free for 19 months off chemotherapy with preserved renal function.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Aniridie
/
Enfant d'âge préscolaire
/
Syndrome WAGR
/
Tumeur de Wilms
/
Parturition
/
Corée
/
Déficience intellectuelle
Limites du sujet:
Humains
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Korean Journal of Pediatrics
Année:
2008
Type:
Article
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