Analysis of the factors affecting the prognosis of surgical patients with intracranial aneurysm / 中华神经医学杂志

ABSTRACT

Objective To analyze the factors affecting the clinical outcomes of surgical patients with intracranial aneurysm(IA).Methods The clinical data of 215 patients undergoing surgeries for IA between May,2002 and May,2007 were retrospectively analyzed.In all these cases,the diagnoses were established according to the results of CT,CT angiography(CTA)and digital subtraction angiography(DSA).With the therapeutic effect as the dependent variable,logistic regression analysis was performed to examine 10 factors that potentially affected the outcome of the patients.Results In all the patients,190(87.7%)were cured,22(10.9%)had mild to moderate disabilities,and 4(1.4%)died.Statistical analysis showed that age,aneurysm location,temporary occlusion of the parent artery,intraoperative aneurysm rupture,and the preoperative scores of Hunt-Hess scale and Fisher scale were correlated to the prognosis of the patients.Such factors as gender,operative time,and times of preoperative subarachnoid hemorrhage and aneurysm size were not found to obviously affect the patients' prognosis.Conclusions The prognosis of surgical patients with 1A is affected by multiple factors,and intraoperative aneurysm rupture is directly associated with the surgical outcome.