Analysis of malignant ovarian germ cell tumor prognosis / 中国现代医生

ABSTRACT

Objective To investigate the clinical features, pathological characteristics and prognostic factors of the ma-lignant ovarian germ cell tumor. Methods There was a retrospective analysis about 31 patients of malignant ovarian germ cell tumor from Jan 2006 to Dec 2011,while clinic and pathological factors were analyzed,and the related litera-ture was prognostic analyzed. Results Nine cases were ovarian teratoma with malignant change in 31 patients. 7 cases were ovarian immature teratoma, 6 cases were ovarian dysgerminoma, 5 cases were yolk sac tumor, 3 cases were em-bryonal carcinoma, 1 patient was ovarian mixed yolk sac tumor and embryonal carcinoma. Multivariate survival analysis showed that operation pathological staging and pathological types were independent prognostic factors affecting overall survival rate for patients (P=0.018 and P=0.021). A variety of different pathological types of malignant ovarian germ cell tumor survival rate, the difference was statistically significant (P=0.049). Conclusion Operation and pathology of malignant ovarian germ cell tumor staging more late, the survival rate of the patients is low. Prognosis of ovarian malig-nant germ cell tumors of different pathological types is different.