Estimating the Prevalence of Treated Epilepsy Using Administrative Health Data and Its Validity: ESSENCE Study
Journal of Clinical Neurology
; : 434-440, 2016.
Article
de En
| WPRIM
| ID: wpr-104824
Bibliothèque responsable:
WPRO
ABSTRACT
BACKGROUND AND PURPOSE: Few of the epidemiologic studies of epilepsy have utilized well-validated nationwide databases. We estimated the nationwide prevalence of treated epilepsy based on a comprehensive medical payment database along with diagnostic validation. METHODS: We collected data on patients prescribed of antiepileptic drugs (AEDs) from the Health Insurance Review and Assessment service, which covers the entire population of Korea. To assess the diagnostic validity, a medical records survey was conducted involving 6,774 patients prescribed AEDs from 43 institutions based on regional clusters and referral levels across the country. The prevalence of treated epilepsy was estimated by projecting the diagnostic validity on the number of patients prescribed AEDs. RESULTS: The mean positive predictive value (PPV) for epilepsy was 0.810 for those prescribed AEDs with diagnostic codes that indicate epilepsy or seizure (Diagnosis-E), while it was 0.066 for those without Diagnosis-E. The PPV tended to decrease with age in both groups, with lower values seen in females. The prevalence was 3.84 per 1,000, and it was higher among males, children, and the elderly. CONCLUSIONS: The prevalence of epilepsy in Korea was comparable to that in other East Asian countries. The diagnostic validity of administrative health data varies depending on the method of case ascertainment, age, and sex. The prescriptions of AEDs even without relevant diagnostic codes should be considered as a tracer for epilepsy.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Orientation vers un spécialiste
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Crises épileptiques
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Études épidémiologiques
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Dossiers médicaux
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Épidémiologie
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Prévalence
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Asiatiques
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Épilepsie
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Ordonnances
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Assurance maladie
Type d'étude:
Observational_studies
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Prevalence_studies
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Risk_factors_studies
Limites du sujet:
Aged
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Child
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Female
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Humans
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Male
Pays comme sujet:
Asia
langue:
En
Texte intégral:
Journal of Clinical Neurology
Année:
2016
Type:
Article