ANCA-negative limited Wegener's granulomatosis / 대한내과학회지
Korean Journal of Medicine
; : S103-S107, 2009.
Article
de Ko
| WPRIM
| ID: wpr-105021
Bibliothèque responsable:
WPRO
ABSTRACT
Wegener's granulomatosis is a very rare autoimmune disease that forms inflammatory granulomas of the upper and lower respiratory tract, and causes necrotizing vasculitis by invading small vessels. Its etiology is uncertain, but antineutrophil cytoplasmic antibody (ANCA) is thought to play an important role in causing the inflammatory granuloma formation and vasculitis. The detection of ANCA is a valuable finding in diagnosing Wegener's granulomatosis. However, in the limited type of Wegener's granulomatosis, which lacks accompanying constitutional symptoms, the diagnostic value of ANCA is minimal, requiring careful interpretation of ANCA-negativity. We report a case diagnosed as limited-type Wegener's granulomatosis through repeated biopsies despite ANCA negativity.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Appareil respiratoire
/
Maladies auto-immunes
/
Vascularite
/
Biopsie
/
Granulomatose avec polyangéite
/
Anticorps anti-cytoplasme des polynucléaires neutrophiles
/
Granulome
langue:
Ko
Texte intégral:
Korean Journal of Medicine
Année:
2009
Type:
Article