Therapeutic Angiogenesis as a Potential Future Treatment Strategy for Erectile Dysfunction
The World Journal of Men's Health
;
: 93-98, 2012.
Article
Dans Anglais
| WPRIM
| ID: wpr-105232
ABSTRACT
The cavernous endothelium plays a crucial role in regulating the tone of the underlying smooth muscle and physiologic penile erection. Recently, the link between erectile dysfunction (ED) and cardiovascular disease was unveiled, and the main etiology of ED was found to be vasculogenic. Although oral phosphodiesterase-5 inhibitors are generally effective for men with ED, such therapies do not cure underlying vasculopathy in the corpus cavernosum tissue. This review addresses current preclinical protein, gene, and cell or stem cell therapies for enhancing cavernous endothelial regeneration and restoring erectile function.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Régénération
/
Cellules souches
/
Érection du pénis
/
Carbonates
/
Maladies cardiovasculaires
/
Agents angiogéniques
/
Endothélium
/
Cyclic Nucleotide Phosphodiesterases, Type 5
/
Hydroxyde d'aluminium
/
Grottes
Limites du sujet:
Humains
/
Mâle
langue:
Anglais
Texte intégral:
The World Journal of Men's Health
Année:
2012
Type:
Article
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