Genetic Heterogeneity of Borrelia burgdorferi Sensu Lato Isolated in Chungju, Korea, by ospC Gene Sequence Analysis
Journal of Bacteriology and Virology
;
: 159-164, 2002.
Article
Dans Anglais
| WPRIM
| ID: wpr-105398
ABSTRACT
Eight Borrelia burgdorferi strains, which had been isolated from Ixodes nipponensis and Apodemus agrarius captured in the Chungju area of Korea, were characterized by ospC gene sequence analysis. Nucleotide sequence similarity among the Chungju strains ranged from 83.6 to 100%. Deduced amino acid sequence similarity of the Chungju strains ranged from 75.4 to 100%. In a molecular phylogenetic analysis, the Chungju strains were separated from B. burgdorferi and B. garinii reference strains, and formed a cluster with B. afzelii reference strains. Three (KK2, KM4, and KK5), two (CJ2 and CJ21), and one (CJ3) Chungju strains formed clusters with OspC serotype 5, OspC serotype 8, and OspC serotype 7 reference strains, respectively. However, two Chungju strains (KK1 and KM10) formed a distinctive cluster that was separated from other strains of B. afzelii reference strains. These results suggest that Chungju strains are very heterogeneous in clonality.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Borrelia
/
Séquence nucléotidique
/
Groupe Borrelia burgdorferi
/
Séquence d'acides aminés
/
Analyse de séquence
/
Hétérogénéité génétique
/
Ixodes
/
Borrelia burgdorferi
/
Murinae
/
Corée
Limites du sujet:
Animaux
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Journal of Bacteriology and Virology
Année:
2002
Type:
Article
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