Factors related to prevalence of colonic polyps in acromegalic patients / 대한내과학회지
Korean Journal of Medicine
;
: 55-60, 2005.
Article
Dans Coréen
| WPRIM
| ID: wpr-106605
ABSTRACT
BACKGROUND:
It has been suggested that acromegalic patients are at increased risk of developing colonic neoplasia. We evaluated the prevalence of colonic neoplasia and the relationships of clinical parameters of acromegalic activity with presence of colonic neoplasia in Korean acromegalic patients.METHODS:
In 30 patients with active acromegaly, colonoscopy was performed at the time of diagnosis. According to the endoscopic findings and histological classifications, the patients were grouped, and a number of clinical parameters of acromegalic activity were compared between those with and without colonic polyps.RESULTS:
Colonic polyps were detected in 17 (56.7%) in the 30 acromegalic patients with colonoscopic examinations; 7 (23.3%) hyperplastic and 10 (33.3%) adenomatous polyps. Those with colonic polyps were significantly older (52.2+/-9.46 years vs. 42.2+/-12.97 years, p=0.02) and also had significantly longer disease duration (11.8+/-7.52 years vs. 5+/-2.20 years, p=0.004) than those without ones. In 21 patients who were more than 40 years old, significant differences were found in disease duration (12.7+/-7.54 years vs. 5.0+/-2.68 years, p=0.026) and serum IGF-1 level (1311.9+/-500.14 ng/mL vs. 715.9+/-330.58 ng/mL, p=0.015) between those with and without colonic polyps.CONCLUSION:
These results suggest that screening colonoscopy should be recommended in acromegalic patients who are more than 40 year-old, have long disease duration or have high serum IGF-1 level.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Acromégalie
/
Facteur de croissance IGF-I
/
Polypes coliques
/
Dépistage de masse
/
Prévalence
/
Coloscopie
/
Classification
/
Côlon
/
Polypes adénomateux
/
Diagnostic
Type d'étude:
Etude diagnostique
/
Étude de prévalence
/
Étude pronostique
/
Facteurs de risque
/
Étude de dépistage
Limites du sujet:
Adulte
/
Humains
langue:
Coréen
Texte intégral:
Korean Journal of Medicine
Année:
2005
Type:
Article
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