3 Cases of Fenoverine-Induced Rhabdomyolysis / 대한신장학회잡지
Korean Journal of Nephrology
;
: 680-685, 2005.
Article
Dans Coréen
| WPRIM
| ID: wpr-106613
ABSTRACT
Fenoverine is a spasmolytic drug. It has been reported as a causative drug for rhabdomyolysis in France and also in Korea. Well known risk factors for fenoverine induced rhabdomyolysis are hepatic dysfunction, renal dysfunction, concomitant use of lipid lowering drug, mitochondrial myopathy, lipid storage myopathy or malignant hyperthermia. We describe the clinical findings of 3 cases of fenoverine-induced rhabdomyolysis. (Case 1) A 78 year-old male patient complained of generalized myalgia after 7 days medication of fenoverine 300 mg, daily. (Case 2) A 72 year-old female who had been on statin medication for 4 years, complained of generalized myalgia and weakness after 1 day medication of 300 mg of fenoverine. (Case 3) A 57 year-old female who was diagnosed with liver cirrhosis, complained of generalized myalgia, after 4 days medication of 300mg of fenoverine. Laboratory and Tc-99m MDP bone scan findings were compatible with rhabdomyolysis in all 3 patients ARF was complicated in case 2 and 3. The renal function improved with supportive care. As far as our knowledge concerned, case 1 is the first report of fenoverine-induced rhabdomyolysis without previously known risk factors. So we suggest when physicians are prescribing fenoverine, careful monitoring of symptoms and signs of rhabdomyolysis should be taken to all patients.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Rhabdomyolyse
/
Médronate de technétium (99mTc)
/
Facteurs de risque
/
Myopathies mitochondriales
/
Inhibiteurs de l'hydroxyméthylglutaryl-CoA réductase
/
Myalgie
/
France
/
Corée
/
Cirrhose du foie
/
Hyperthermie maligne
Type d'étude:
Etude d'étiologie
/
Facteurs de risque
Limites du sujet:
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Asie
/
Europe
langue:
Coréen
Texte intégral:
Korean Journal of Nephrology
Année:
2005
Type:
Article
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