A Case of Skin Sclerosis Associated with Docetaxel Chemotherapy for Non-Small Cell Lung Cancer
Journal of Rheumatic Diseases
;
: 198-201, 2013.
Article
Dans Coréen
| WPRIM
| ID: wpr-107350
ABSTRACT
A 64-year-old woman was diagnosed with non-small cell lung cancer. Her disease was stage 4 (T2N2M1) with squamous cell carcinoma. She had been treated with docetaxel and carboplatin. After a completion of 11 cycle of chemotherapy, edema appeared on both feet and had spread rapidly up to the pretibial area without response to diuretics. Sclerotic changes and pigmentation followed but both knees and other parts of the body were spared. There was no evidence of vascular occlusions. On serologic tests, antinuclear, anti-centromere, and anti-topoisomerase I antibodies were all negative. A skin biopsy revealed diffuse infiltration of lymphocytes and discretely thickened collagen bundles in the superficial dermis. After discontinuing docetaxel chemotherapy, she was treated with prednisolone and D-penicillamine and sclerotic changes on the lower legs were improved.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pénicillamine
/
Sclérose
/
Peau
/
Biopsie
/
Pigmentation
/
Prednisolone
/
Tests sérologiques
/
Lymphocytes
/
Carcinome épidermoïde
/
Glycogénose de type VI
Type d'étude:
Etude diagnostique
Limites du sujet:
Femelle
/
Humains
langue:
Coréen
Texte intégral:
Journal of Rheumatic Diseases
Année:
2013
Type:
Article
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