Papillary Thyroid Carcinoma Manifesting as an Autonomously Functioning Thyroid Nodule
Endocrinology and Metabolism
; : 59-62, 2012.
Article
de En
| WPRIM
| ID: wpr-107385
Bibliothèque responsable:
WPRO
ABSTRACT
Hyperfunctioning thyroid carcinoma is very rare. Hence, radionuclide imaging of thyroid hot nodules usually suggests a benign tumor, and less than 4% of cases have been reported as malignant. We would like to present a case of a hyperfunctioning papillary thyroid carcinoma that was initially treated with radioactive iodine. A 58-year-old woman was referred to our hospital for palpable thyroid nodule and a 5-kg weight loss within 6 months. Thyroid function test revealed thyrotoxicosis, and thyroid autoantibodies were absent. 99mTc thyroid scintigraphy showed a 2 x 2 cm-sized hyperactive hot nodule at the left lobe. Despite radioactive iodine treatment with a dose of 10 mCi 131I, thyroid function did not improve. Fine needle aspiration revealed papillary thyroid cancer. The patient underwent total thyroidectomy. Although clinical features and thyroid scans suggest a benign nodule, the possibility of malignancy should not be ruled out. Malignant thyroid hot nodules are rare; however, its possibility should be taken into account. Therefore, we suggest that ruling out malignancy by existing diagnostic guidelines can misdiagnose even a typical case with benign features. As thyroid nodule detection is getting sensitive and accurate, we present this case to discuss whether additional diagnostic approaches would be necessary for thyroid nodules.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Autoanticorps
/
Tests de la fonction thyroïdienne
/
Glande thyroide
/
Thyroïdectomie
/
Thyréotoxicose
/
Tumeurs de la thyroïde
/
Carcinomes
/
Perte de poids
/
Nodule thyroïdien
/
Cytoponction
Type d'étude:
Guideline
Limites du sujet:
Female
/
Humans
langue:
En
Texte intégral:
Endocrinology and Metabolism
Année:
2012
Type:
Article