Skin and Soft Tissue Infection due to Rapidly Growing Mycobacteria: Case Series and Literature Review / 감염과화학요법
Infection and Chemotherapy
;
: 85-93, 2013.
Article
Dans Anglais
| WPRIM
| ID: wpr-108240
ABSTRACT
BACKGROUND:
Nontuberculous mycobacteria (NTM) are ubiquitous in soil and water. Most NTM cause disease in humans only rarely unless some aspect of host defense is impaired. Recently, rapidly growing mycobacteria (RGM) is not uncommon, and the prevalence of RGM infection has been increasing. RGM causes a wide spectrum of pulmonary and extrapulmonary diseases and has been shown as an important source for opportunistic infection. MATERIALS ANDMETHODS:
We report 5 patients of skin and soft tissue infection due to RGM in tertiary medical center in Jeju Island and analyzed 21 patients of skin and soft tissue infection due to RGM in Republic of Korea. Clinical, microbiological and epidemiological data were collected from each patient. NTM isolates were identified using conventional and molecular methods including 16S rDNA gene sequencing.RESULTS:
The mean age of the RGM patients (n=26) was 54.9 +/- 15.9 years and 73% were women. Mycobacterium fortuitum complex was the most common (12/26). Antimicrobial resistance for clarithromycin and quinolone were 12% and 60%, respectively. Clarithromycin based therapy was done in 46%. The mean duration of treatment was 21.2 +/- 8.7 weeks.CONCLUSIONS:
Many cases can be cured after therapy for 4-7 month with at least 2 or 3 antibiotics according to in vitro susceptibility. Recent increasing of NTM cases suggests that species and subspecies identification is epidemiologically important, especially related to medical procedure, and surgery.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Peau
/
Sol
/
ADN ribosomique
/
Prévalence
/
Clarithromycine
/
Infections des tissus mous
/
Mycobacterium fortuitum
/
République de Corée
/
Antibactériens
/
Mycobactéries non tuberculeuses
Type d'étude:
Étude de prévalence
Limites du sujet:
Femelle
/
Humains
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Infection and Chemotherapy
Année:
2013
Type:
Article
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