Transfusion Strategy of RhD-negative/variant Patients in the Korean Population
Laboratory Medicine Online
; : 89-93, 2017.
Article
Dans Ko
| WPRIM
| ID: wpr-110645
Responsable en Bibliothèque :
WPRO
ABSTRACT
The prevalence of RhD-negative individuals in the Korean population is approximately 0.15-0.30% and the supply of RhD-negative blood often faces potential shortage. Furthermore, 15-17% of serologically RhD-negative Korean individuals were revealed to be DEL variants and should be treated as RhD-positive when being considered as blood donors. This change is expected to result in a further shortage of RhD-negative blood supply, whereas surplus DEL variant blood stock is created. Therefore, it is now required to amend blood donation and supply policies, and transfusion strategies. In this review, a new transfusion strategy for patients with RhD-negative or variant blood in Korea is discussed, with particular interest in women of child-bearing age, patients with anti-D, and Asia type DEL (c.1227G>A) variants.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Asie
/
Donneurs de sang
/
Prévalence
/
Corée
Type d'étude:
Prevalence_studies
Limites du sujet:
Female
/
Humans
Pays comme sujet:
Asia
langue:
Ko
Texte intégral:
Laboratory Medicine Online
Année:
2017
Type:
Article