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Colorectal Neoplasm in Asymptomatic Average-risk Koreans: The KASID Prospective Multicenter Colonoscopy Survey
Gut and Liver ; : 35-40, 2009.
Article Dans Anglais | WPRIM | ID: wpr-111175
ABSTRACT
BACKGROUND/

AIMS:

The incidence of colorectal cancer is increasing in Korea, but the epidemiology of colorectal neoplasm is not clearly defined. We aimed to elucidate the prevalence of colorectal neoplasm in average-risk Koreans and explore the underlying risk factors.

METHODS:

A large-scale, multicenter, prospective study was conducted. Of the 19,460 subjects who underwent colonoscopy at 11 university hospitals, we analyzed 3,951 consecutive asymptomatic adults with no risk factors for colorectal cancer.

RESULTS:

The subjects were aged 52.1+/-11.6 years (mean+/-SD) and 60.1% of them were men. The prevalences of colorectal neoplasm and advanced neoplasm were 33.3% and 2.2%, respectively. The prevalence of a neoplasm increased with age (trend p<0.001) and was higher in males (p<0.001). The prevalence of a proximal neoplasm was higher in subjects with a distal neoplasm than in those without a distal neoplasm (11.9% vs. 5.4%, p<0.001). However, 150 (52.1%) of the 288 subjects with a proximal neoplasm had no distal neoplasm.

CONCLUSIONS:

The overall prevalence of colorectal neoplasm in asymptomatic average-risk Koreans is comparable with that in Western countries. Being male and older are associated with a higher risk of colorectal neoplasm. Over half of proximal neoplasms are not associated with any distal sentinel lesions.
Sujets)

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Pyréthrines / Tumeurs colorectales / Dépistage de masse / Incidence / Prévalence / Études prospectives / Facteurs de risque / Coloscopie / Hôpitaux universitaires / Corée Type d'étude: Essai clinique contrôlé / Etude d'étiologie / Etude d'incidence / Étude observationnelle / Étude de prévalence / Étude pronostique / Facteurs de risque / Étude de dépistage Limites du sujet: Adulte / Adulte très âgé / Humains / Mâle Pays comme sujet: Asie langue: Anglais Texte intégral: Gut and Liver Année: 2009 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Pyréthrines / Tumeurs colorectales / Dépistage de masse / Incidence / Prévalence / Études prospectives / Facteurs de risque / Coloscopie / Hôpitaux universitaires / Corée Type d'étude: Essai clinique contrôlé / Etude d'étiologie / Etude d'incidence / Étude observationnelle / Étude de prévalence / Étude pronostique / Facteurs de risque / Étude de dépistage Limites du sujet: Adulte / Adulte très âgé / Humains / Mâle Pays comme sujet: Asie langue: Anglais Texte intégral: Gut and Liver Année: 2009 Type: Article