Colorectal Neoplasm in Asymptomatic Average-risk Koreans: The KASID Prospective Multicenter Colonoscopy Survey
Gut and Liver
;
: 35-40, 2009.
Article
Dans Anglais
| WPRIM
| ID: wpr-111175
ABSTRACT
BACKGROUND/AIMS:
The incidence of colorectal cancer is increasing in Korea, but the epidemiology of colorectal neoplasm is not clearly defined. We aimed to elucidate the prevalence of colorectal neoplasm in average-risk Koreans and explore the underlying risk factors.METHODS:
A large-scale, multicenter, prospective study was conducted. Of the 19,460 subjects who underwent colonoscopy at 11 university hospitals, we analyzed 3,951 consecutive asymptomatic adults with no risk factors for colorectal cancer.RESULTS:
The subjects were aged 52.1+/-11.6 years (mean+/-SD) and 60.1% of them were men. The prevalences of colorectal neoplasm and advanced neoplasm were 33.3% and 2.2%, respectively. The prevalence of a neoplasm increased with age (trend p<0.001) and was higher in males (p<0.001). The prevalence of a proximal neoplasm was higher in subjects with a distal neoplasm than in those without a distal neoplasm (11.9% vs. 5.4%, p<0.001). However, 150 (52.1%) of the 288 subjects with a proximal neoplasm had no distal neoplasm.CONCLUSIONS:
The overall prevalence of colorectal neoplasm in asymptomatic average-risk Koreans is comparable with that in Western countries. Being male and older are associated with a higher risk of colorectal neoplasm. Over half of proximal neoplasms are not associated with any distal sentinel lesions.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pyréthrines
/
Tumeurs colorectales
/
Dépistage de masse
/
Incidence
/
Prévalence
/
Études prospectives
/
Facteurs de risque
/
Coloscopie
/
Hôpitaux universitaires
/
Corée
Type d'étude:
Essai clinique contrôlé
/
Etude d'étiologie
/
Etude d'incidence
/
Étude observationnelle
/
Étude de prévalence
/
Étude pronostique
/
Facteurs de risque
/
Étude de dépistage
Limites du sujet:
Adulte
/
Adulte très âgé
/
Humains
/
Mâle
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Gut and Liver
Année:
2009
Type:
Article
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