Using Sirolimus for Posttransplant Management and Reduction of Tuberous Sclerosis Complex Progression in a Patient with End Stage Renal Disease Caused by Tuberous Sclerosis Complex / 대한이식학회지
The Journal of the Korean Society for Transplantation
;
: 241-245, 2014.
Article
Dans Coréen
| WPRIM
| ID: wpr-111534
ABSTRACT
Tuberous sclerosis complex (TSC) is a neurocutaneous disease characterized by the formation of hamartomas in multiple organs. TSC can show lesions including facial angiofibroma, shagreen patch on the skin, cortical tuber, subependymal nodule, astrocytoma in the brain, cardiac rhabdomyoma, and renal angiomyolipoma. In particular, renal angiomyolipoma may be a cause of end-stage renal disease (ESRD). On the other hand, sirolimus has regulatory effects on cellular growth and proliferation via its inhibitory effect on a protein, mammalian target of rapamycin. We report on a case of an 18-year-old male who underwent renal transplantation due to ESRD induced by TSC. Sirolimus played a role in successful treatment of TSC and effective immunosuppression for transplantation.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Rhabdomyome
/
Astrocytome
/
Peau
/
Complexe de la sclérose tubéreuse
/
Encéphale
/
Immunosuppression thérapeutique
/
Transplantation rénale
/
Angiomyolipome
/
Angiofibrome
/
Sirolimus
Limites du sujet:
Adolescent
/
Humains
/
Mâle
langue:
Coréen
Texte intégral:
The Journal of the Korean Society for Transplantation
Année:
2014
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS