Review of Biological Network Data and Its Applications
Genomics & Informatics
; : 200-210, 2013.
Article
Dans En
| WPRIM
| ID: wpr-11254
Responsable en Bibliothèque :
WPRO
ABSTRACT
Studying biological networks, such as protein-protein interactions, is key to understanding complex biological activities. Various types of large-scale biological datasets have been collected and analyzed with high-throughput technologies, including DNA microarray, next-generation sequencing, and the two-hybrid screening system, for this purpose. In this review, we focus on network-based approaches that help in understanding biological systems and identifying biological functions. Accordingly, this paper covers two major topics in network biology: reconstruction of gene regulatory networks and network-based applications, including protein function prediction, disease gene prioritization, and network-based genome-wide association study.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Biologie
/
Dépistage de masse
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Séquençage par oligonucléotides en batterie
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Réseaux de régulation génique
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Étude d'association pangénomique
/
Ensemble de données
Type d'étude:
Screening_studies
langue:
En
Texte intégral:
Genomics & Informatics
Année:
2013
Type:
Article