Clinicopathologic study of ovarian granulosa cell tumors / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
; : 429-436, 2009.
Article
de Ko
| WPRIM
| ID: wpr-11289
Bibliothèque responsable:
WPRO
ABSTRACT
OBJECTIVE: The aim of this study was to evaluate the clinicopathologic characteristics of granulosa cell tumor of the ovary (OGCT). METHODS: We retrospectively reviewed the medical records of 27 patients with OGCT at our hospitals from January 1995 to December 2003. RESULTS: The mean age was 48.3 years (24~70) and mean follow up period was 56.7 months (12~102). The most common symptom was vaginal bleeding (n=11, 40.7%). The tumors were ranging from 3 cm to 21 cm in diameter (mean: 9.9). Post-surgical FIGO stage was stage I in 20 (74.1%), stage II in 6 (22.2%), and stage III in 1 (3.7%). Endoemetrial samples were available in 21 patients and the results were endometrial carcinoma in 1 and endometrial hyperplasias in 5. Staging operation was performed in 17, unilateral salpingo-oophorectomy in 6, total hysterectomy and bilateral salpingo-oophorectomy in 2, and fertility sparing operation in 2. Postoperative chemotherapy was administered in 13 patients (48.2%). Two patients had recurred and recurrence rate was 7.4% (2/27). Two recurred patients finally died of the disease at 42 months and 103 months after first operation respectively. During follow-up period, 2 patients had 3 pregnancies and all of them delivered at term. CONCLUSION: These results shows that most OGCT is detected in early stage and have relatively excellent survival. However, because OGCT is a slow-growing tumor and has a late recurrence, long time follow-up is required.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Ovaire
/
Récidive
/
Hémorragie utérine
/
Dossiers médicaux
/
Études rétrospectives
/
Études de suivi
/
Tumeurs de l'endomètre
/
Hyperplasie endométriale
/
Fécondité
/
Tumeur de la granulosa
Type d'étude:
Observational_studies
/
Prognostic_studies
Limites du sujet:
Female
/
Humans
/
Pregnancy
langue:
Ko
Texte intégral:
Korean Journal of Obstetrics and Gynecology
Année:
2009
Type:
Article