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Pregnancy outcomes of antenatally diagnosed congenital cystic adenomatoid malformation of lung / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology ; : 413-419, 2009.
Article Dans Coréen | WPRIM | ID: wpr-11291
ABSTRACT

OBJECTIVE:

To determine the accuracy of antenatal diagnosis, pregnancy outcome and the predictors for adverse outcome in antenatally diagnosed congenital cystic adenomatoid malformation (CCAM).

METHODS:

A retrospective review was performed on a total of 32 patients with antenatally diagnosed CCAM between January, 1999 and June, 2008.

RESULTS:

Of 32 cases with antenatally diagnosed CCAM, 8 patients were lost to follow-up. In remaining 24 patients, postnatal histologic examination and/or radiologic study showed definitive diagnostic features of CCAM (n=20), pulmonary sequestration (n=3) and congenital lobar emphysema (n=1). The accuracy of antenatal diagnosis was 83.3% (20/24). The rate of presence of hydrops and/or ascites was 10% (2/20) in those with CCAM confirmed postnatally. Of the 2 patients with ascites and/or hydrops, thoraco-amniotic (TA) shunt was performed in one case with hydrops and termination was done in the other case. All of the 15 cases with ongoing pregnancy were delivered at term, except one with TA-shunt who was born at 33(+3) weeks of gestation (mean gestational age at birth+/-standard deviation; 39.6+/-2.2 weeks, mean birth weight; 3,200+/-500 gram). All 15 neonates were discharged alive without any complication. Antenatal sonographic microcystic lesion was associated with postnatal histologic type III lesion [5 type III lesions in 7 microcystitc cases (71.4%) vs. no type III lesion in 13 macrocystic cases (0%), P<0.01].

CONCLUSION:

The incidence of ascites and/or hydrops was 10% (2/20) in fetuses with CCAM. Antenatally diagnosed CCAM has an excellent prognosis in the absence of signs of ascites and/or hydrops.
Sujets)

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Diagnostic prénatal / Pronostic / Ascites / Emphysème pulmonaire / Issue de la grossesse / Malformation congénitale kystique adénomatoïde du poumon / Séquestration bronchopulmonaire / Incidence / Études rétrospectives / Âge gestationnel Type d'étude: Etude diagnostique / Etude d'incidence / Étude observationnelle / Étude pronostique Limites du sujet: Femelle / Humains / Nouveau-né / Grossesse langue: Coréen Texte intégral: Korean Journal of Obstetrics and Gynecology Année: 2009 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Diagnostic prénatal / Pronostic / Ascites / Emphysème pulmonaire / Issue de la grossesse / Malformation congénitale kystique adénomatoïde du poumon / Séquestration bronchopulmonaire / Incidence / Études rétrospectives / Âge gestationnel Type d'étude: Etude diagnostique / Etude d'incidence / Étude observationnelle / Étude pronostique Limites du sujet: Femelle / Humains / Nouveau-né / Grossesse langue: Coréen Texte intégral: Korean Journal of Obstetrics and Gynecology Année: 2009 Type: Article