A case of Apert's Syndrome(Acrocophalosyndactyly) with Fibroblast Growth Factor Receptor 2 Exon IIIa Mutation
Journal of the Korean Pediatric Society
; : 1006-1011, 2000.
Article
de Ko
| WPRIM
| ID: wpr-113878
Bibliothèque responsable:
WPRO
ABSTRACT
Apert syndrome is an uncommon congenital disorder characterized by malformation of the skull in association with symmetrical syndactyly of both hands and feet. This syndrome is autosornal dominant. The original description was presented by Apert in 1906. Since then more than 200 cases have been reported in the world. Recently, we experienced a case of newhorn male infant with congenital anomalies of the skull and extremities. Molecular biologically, he was found to have Ser252Try mutation in the FGFR2 exonIIIa. A brief review of literature was made.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Crâne
/
Acrocéphalosyndactylie
/
Récepteur facteur croissance fibroblaste
/
Syndactylie
/
Récepteur FGFR2
/
Membres
/
Facteurs de croissance fibroblastique
/
Fibroblastes
/
Pied
/
Main
Limites du sujet:
Humans
/
Infant
/
Male
langue:
Ko
Texte intégral:
Journal of the Korean Pediatric Society
Année:
2000
Type:
Article