Surgical Management and Long-Term Outcome of Bronchial Carcinoids / 대한흉부외과학회지
The Korean Journal of Thoracic and Cardiovascular Surgery
;
: 381-386, 2002.
Article
Dans Coréen
| WPRIM
| ID: wpr-114036
ABSTRACT
BACKGROUND:
Bronchial carcinoids account for approximately 2% of all pulmonary tumor and consist of typical carcinoids and atypical carcinoids. An atypical carcinoid is considered to be an intermediate form of tumor between a low-grade malignant typical carcinoid and a high-grade malignant small cell lung carcinoma. There is still controversy with regard to the extent of resection and the value of systemic adjuvant therapy in atypical carcinoids. We performed a retrospective review of our experiences at Severance Hospital. MATERIAL ANDMETHOD:
Between 1990 and 2000, 15 patients with bronchial carcinoids were operated, and 5 of these had atypical carcinoids. Histologic diagnosis was established on the criteria of WHO/IASLC(1999).RESULT:
There were 3 pneumonectomies, 11 lobectomies, and 1 segmentectomy. In typical carcinoids, one patient had regional lymph node metastasis, and 3 patients in atypical carcinoids had mediastinal lymph node metastases. Distant metastases developed in one patient of typical carcinoid, but developed in 4 patients of atypical carcinoids(p=0.0017). The 5-year survival rate in patients with atypical carcinoids was 20%, versus the 100% 5-year survival rate observed in patients with typical carcinoids(p=0.0039).CONCLUSION:
In atypical carcinoids, because of many lymph node metastases on diagnosis and a low long-term survival rate, lobectomy constitutes a mininal procedure. Adjuvant systemic therapy is recommended for patients with lymph node and distant metastasis.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pneumonectomie
/
Tumeur carcinoïde
/
Mastectomie partielle
/
Taux de survie
/
Études rétrospectives
/
Diagnostic
/
Carcinome pulmonaire à petites cellules
/
Noeuds lymphatiques
/
Métastase tumorale
Type d'étude:
Etude diagnostique
/
Étude observationnelle
Limites du sujet:
Humains
langue:
Coréen
Texte intégral:
The Korean Journal of Thoracic and Cardiovascular Surgery
Année:
2002
Type:
Article
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