Transfusion Premedication: A Single Center Study / 대한수혈학회지
Korean Journal of Blood Transfusion
;
: 121-127, 2013.
Article
Dans Coréen
| WPRIM
| ID: wpr-117797
ABSTRACT
BACKGROUND:
Acute transfusion reaction occurs during or within a few hours of transfusion with 0.5~3% of blood transfusion. Febrile non-hemolytic transfusion reactions (FNHTRs) and allergic transfusion reactions (ATRs) are the most common transfusion reactions. Premedication with acetaminophen and diphenhydramine has been used to prevent these reactions in 50~80% of transfusions. The purpose of this study was to describe the frequency of premedication and FNHTRs and ATRs according to premedication in Korea.METHODS:
Between January 1 and 31, 2013, analysis of the first transfusion was performed retrospectively with chart review. A total of 549 cases were analyzed with regard to product of blood, care area, premedication, and FNHTRs and ATRs.RESULTS:
Premedication was administered in 88.2% (484/549) of transfusions; 4 mg chlorphenamine, a well-known antihistamine, was used as premedication in all cases. Occurrence of FNHTRs was 7.7% without premedication and 3.7% with premedication. Occurrence of ATRs was 0% without premedication and 0.8% with premedication. The frequency of premedication was related to care area but not blood products.CONCLUSION:
Premedication use was more frequent than previously reported. However, the sample size in this study is small; therefore, conduct of further prospective multicenter studies is needed.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Prémédication
/
Incompatibilité sanguine
/
Transfusion sanguine
/
Chlorphénamine
/
Études rétrospectives
/
Taille de l'échantillon
/
Diphénhydramine
/
Acétaminophène
Type d'étude:
Étude observationnelle
langue:
Coréen
Texte intégral:
Korean Journal of Blood Transfusion
Année:
2013
Type:
Article
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