Estimation of Joint Risks for Developing Uterine Cervix Cancer in Korea / 예방의학회지
Korean Journal of Preventive Medicine
;
: 263-268, 2002.
Article
Dans Coréen
| WPRIM
| ID: wpr-120597
ABSTRACT
OBJECTIVE:
This study was aiming at estimating the joint effects of various risk factors associated with uterine cervix cancer in Korea.METHODS:
Data obtained from a case-control study were analyzed with a multiplicative model.RESULTS:
After adjustment for age and husband's educational attainments, the family history of cervical cancer (OR=2.1, 95% CI=1.2-3.9), unstable marital status due to separation, by death or divorce, etc. (OR=2.8, 95% CI=1.7-4.6), and a large number of deliveries (> or = 3 vs. nulliparous OR=6.5, 95% CI=1.4-29.9) increased the risk of uterine cervix cancer. Conversely, first sexual intercourse at an older age (> or = 25 years vs. <19 years OR=0.4, 95% CI=0.2-0.6) and husband's circumcision (OR=0.7, 95% CI=0.5-1.0) decreased the risk. In the multiplicative model, the highest joint risk (OR=39.2, 95% CI 5.9-258.9) was observed in women with a family history of uterine cervical cancer, an unstable marital status, where the ex-husband was not circumcised, with 3 or more delivery experiences, and having her first sexual intercourse when younger than 19 years of age. However, women without a family history of uterine cervix cancer, married to a circumcised husband, having had her first sexual intercourse at 25 years or older, and nulliparous, showed the lowest joint effect (OR=0.3, 95% CI=0.1-0.5).CONCLUSION:
As carcinogenesis is a complex action involving various factors, we consider a joint effects approach to be appropriate in an epidemiological study on risk factors for uterine cervix neoplasms.cervix neoplasm.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Divorce
/
Études épidémiologiques
/
Études cas-témoins
/
Tumeurs du col de l'utérus
/
Col de l'utérus
/
Facteurs de risque
/
Modèles statistiques
/
Circoncision masculine
/
Situation de famille
/
Coït
Type d'étude:
Etude d'étiologie
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Asie
langue:
Coréen
Texte intégral:
Korean Journal of Preventive Medicine
Année:
2002
Type:
Article
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