Antimicrobial Susceptibility Patterns of Legionella isolates in the Environment and in Patients / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 28-33, 2010.
Article
Dans Coréen
| WPRIM
| ID: wpr-121790
ABSTRACT
BACKGROUND:
Antimicrobial susceptibility of Legionella spp. has rarely been studied in Korea. Therefore, we aimed to determine the susceptibility of Legionella spp. to various antibiotics.METHODS:
We assessed the antimicrobial susceptibility of 66 environmental and clinical Legionella isolates collected between January 2001 and December 2008 from Korea and Japan. The minimum inhibitory concentrations (MICs) of 6 antibiotics, namely, azithromycin, ciprofloxacin, clarithromycin, clindamycin, gatifloxacin, and gemifloxacin were determined by the broth microdilution method using buffered starch yeast extract broth.RESULTS:
The MIC ranges of the 6 antibiotics used against the Legionella isolates were as follows 0.004-0.062 microgram/mL (azithromycin), 0.002-0.5 microgram/mL (ciprofloxacin), 0.004-0.5 microgram/mL (clarithromycin), 0.12-4 microgram/mL (clindamycin), 0.002-0.12 microgram/mL (gatifloxacin), and 0.008-1 microgram/mL (gemifloxacin).CONCLUSIONS:
Legionella spp. isolates from Korea and Japan were most susceptible to gatifloxacin. Azithromycin, clarithromycin, ciprofloxacin, and gemifloxacin were also effective for treating legionellosis.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Légionellose
/
Legionella
/
Clindamycine
/
Ciprofloxacine
/
Tests de sensibilité microbienne
/
Clarithromycine
/
Azithromycine
/
Fluoroquinolones
/
Résistance bactérienne aux médicaments
/
Antibactériens
Limites du sujet:
Humains
langue:
Coréen
Texte intégral:
The Korean Journal of Laboratory Medicine
Année:
2010
Type:
Article
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