Autoimmune hemolytic anemia during PEG-interferon and ribavirin treatment for hepatitis C / 대한내과학회지
Korean Journal of Medicine
;
: 226-230, 2010.
Article
Dans Coréen
| WPRIM
| ID: wpr-121803
ABSTRACT
The current best treatment for HCV infection is combination therapy with PEG-interferon and ribavirin. This combination therapy has markedly increased the number of sustained virologic responders but is associated with various side effects, especially hematological abnormalities. We recently experienced a 45-year-old man who developed PEG-interferon induced autoimmune hemolytic anemia (AIHA) and retinal premacular hemorrhage. The worsening hemolysis after ribavirin withdrawal and exclusion of other causes implicated PEG-interferon as the cause of the AIHA. To the best of our knowledge, this is the first case reported from Korea. Treatment with PEG-interferon requires careful follow-up, as it can induce or exacerbate autoimmune diseases.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Rétinal
/
Ribavirine
/
Maladies auto-immunes
/
Hémorragie de la rétine
/
Études de suivi
/
Hépatite C
/
Hépatite C chronique
/
Hémolyse
/
Hémorragie
/
Hépatite
Type d'étude:
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Humains
Pays comme sujet:
Asie
langue:
Coréen
Texte intégral:
Korean Journal of Medicine
Année:
2010
Type:
Article
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