Factors Influencing the Serum Bilirubin Level in Air Force Pilots / 항공우주의학회지

ABSTRACT

BACKGROUND: The Republic of Korea Air Force (ROKAF) makes its pilots undergo regular aero-medical checkups. About 15% of the pilots undergoing this check-up show increased serum bilirubin levels without any abnormality in other liver function test items, and even reexamination is required for those with a marked increase. In this study, we investigated the factors associated with increased serum bilirubin. METHODS: Questionnaires and blood tests were used for the ROKAF pilots who visited the Aerospace Medical Center for the aero-medical check-up. Various information from the questionnaire and blood test was statistically analyzed to identify the factors associated with increased bilirubin. RESULTS: In univariate analysis, age, fasting > or =12 hours, exercise in the last 3 days, and last alcohol intake > or = 120 g were statistically associated with increased serum bilirubin. In multivariate analysis, fasting > or =12 hours, exercise in the last 3 days, and last alcohol intake > or = 120 g were independent risk factors significantly associated with increased bilirubin. CONCLUSION: Prolonged fasting, recent exercise and drinking were associated with increased serum bilirubin as previously known. Pilots expecting regular aero-medical check-up should avoid intense exercise and drinking in order to get accurate blood test results.