Polymorphism and Haplotypes of 10 Y-STR Loci in Koreans / 대한법의학회지
Korean Journal of Legal Medicine
;
: 62-72, 2003.
Article
Dans Coréen
| WPRIM
| ID: wpr-122671
ABSTRACT
Ten Y chromosomal STRs (DYS434, DYS435, DYS437, DYS438, DYS439, DYS441, DYS442, DYS443, DYS444, DYS445) have been typed in 1159 Korean males for the purpose of application to male identification, population genetics and evolution study. Multiplex PCR method was used in amplifying simultaneously these loci. In each locus, 3-8 allele were observed, and no 'interallele' was observed. The gene diversity varied from 0.3131 at DYS435 to 0.7179 at DYS441. Among 610 father-son pairs, mutation was observed 2 cases in DYS434, 1 case in DYS435, 3 cases in DYS437, 1 case in DYS439, 2 cases in DYS441, 1 case in DYS442 and 4 cases in DYS444. No two or more simultaneous mutations were identified in one father-son family pair. In 1159 Korean males, 641 different haplotypes were observed, and 488 haplotypes were not shared by others. The haplotype diversity was 0.9911, Probability of Identity was 0.0098. When using the ten loci together with DYS19, DYS385, DYS388, DYS389, DYS390, DYS391, DYS392, DYS393 which were already used in the Department of Forensic Medicine, College of Medicine, Seoul National University, the haplotype diversity was 0.9997, Probability of Identity was 0.0012.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Haplotypes
/
Allèles
/
Réaction de polymérisation en chaine multiplex
/
Séoul
/
Médecine légale
/
Génétique des populations
Limites du sujet:
Humains
/
Mâle
Pays comme sujet:
Asie
langue:
Coréen
Texte intégral:
Korean Journal of Legal Medicine
Année:
2003
Type:
Article
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