Magnetic resonance imagining findings of the white matter abnormalities in the brain of very-low-birth-weight infants / 소아과
Korean Journal of Pediatrics
;
: 1127-1135, 2009.
Article
Dans Coréen
| WPRIM
| ID: wpr-123715
ABSTRACT
PURPOSE:
To observe the abnormal white matter findings on the magnetic resonance imaging (MRI) scans of very-low-birth-weight (VLBW) infant brains at term-equivalent age and to determine the clinical risk factors for the development of periventricular leukomalacia (PVL).METHODS:
In all, MRI was performed in 98 VLBW infants and the white matter abnormalities were observed. Clinical risk factors for cystic and noncystic PVL were determined.RESULTS:
MRI scans of 74 infants (75.5%) showed diffuse excessive high signal intensity (DEHSI) in the periventricular white matter, 17 (17.3%) lateral ventricle dilation, 5 (5.1%) and 11 (11.2%) focal punctate lesions and cystic changes in the periventricular white matter, respectively, 9 (9.1%), germinal layer hemorrhage (GLH) or subependymal cysts 3 (3.1%) intraventricular hemorrhage (>grade 2) 2 (2.0%) posthemorrhagic hydrocephalus and 2 (2.0%) periventricular hemorrhagic infarct. Gestational age (GA), 1-minute Apgar score, Clinical Risk Index for Babies-II (CRIB-II) score, and inotrope use, and GA, CRIB-II score, postnatal steroid administration, inotrope use, and abnormal white blood cell (WBC) count at admission were related to cystic PVL and noncystic PVL development, respectively (P<0.05). However, in logistic regression analysis, CRIB-II (odds ratio, 1.63, 295% confidence interval, 1.15-2.30 P=0.006) for cystic PVL, and GA (odds ratio 0.90, 95% confidence interval, 0.82-9.99 P=0.036) for noncystic PVL were only significant independently.CONCLUSION:
White matter abnormalities could be observed on MRI scans of the VLBW infant brains at term-equivalent age, and CRIB-II and GA were only independently significant for cystic and noncystic PVL development, respectively.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Score d'Apgar
/
Leucomalacie périventriculaire
/
Encéphale
/
Imagerie par résonance magnétique
/
Spectroscopie par résonance magnétique
/
Modèles logistiques
/
Facteurs de risque
/
Âge gestationnel
/
Nourrisson très faible poids naissance
/
Ventricules latéraux
Type d'étude:
Etude diagnostique
/
Etude d'étiologie
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Humains
/
Bébé
/
Nouveau-né
langue:
Coréen
Texte intégral:
Korean Journal of Pediatrics
Année:
2009
Type:
Article
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