The effect of body mass index of on the outcome of in vitro fertilization and embryo transfer in patients with polycystic ovary syndrome / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
;
: 75-82, 2009.
Article
Dans Coréen
| WPRIM
| ID: wpr-124408
ABSTRACT
OBJECTIVE:
This study was performed to evaluate the effect of body mass index (BMI) on the outcome of in vitro fertilization and embryo transfer (IVF-ET) in patients with polycystic ovary syndrome (PCOS).METHODS:
Ninety-six patients with PCOS who completed their first cycle of IVF-ET were included in this retrospective study. All patients were stimulated by GnRH antagonist multi-dose protocol. The patients were divided into one of two groups on the basis of BMI > or =23 kg/m2 vs. BMI or =23kg/m2 were divided into patient group with 23 or =25 kg/m2, and these three groups were also compared in regard to the outcome of IVF-ET.RESULTS:
The total amount and duration of rhFSH administration were significantly higher in PCOS women with BMI > or =23 kg/m2 than in those with BMI or =23 kg/m2 (17.4% vs 7.8%, P=0.024). When compared three group divided on the basis of BMI or =25 kg/m2, similar results were showed in women with BMI > or =25 kg/m2, although implantation rate in women with BMI > or =25 kg/m2 was lower with borderline significance (P=0.069).CONCLUSION:
Obesity (BMI > or =23 kg/m2) has a detrimental effect on implantation rate and is associated with the increased total amount and duration of rhFSH administration for ovarian stimulation in IVF-ET cycle. Consequently BMI may be a predictor for IVF outcomes in patients with PCOS.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Induction d'ovulation
/
Syndrome des ovaires polykystiques
/
Fécondation in vitro
/
Indice de masse corporelle
/
Études rétrospectives
/
Hormone de libération des gonadotrophines
/
Transfert d'embryon
/
Structures de l'embryon
/
Obésité
Type d'étude:
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Femelle
/
Humains
langue:
Coréen
Texte intégral:
Korean Journal of Obstetrics and Gynecology
Année:
2009
Type:
Article
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